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Maintenance phase: Once the loading phase is complete, patients transition to maintenance therapy with 1 mg hydroxocobalamin intramuscularly every two to three months for life

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Nocella C, D'Amico A, Cammisotto V, Bartimoccia S, Castellani V, Loffredo L, et al

L., Wilkinson, D., Smith, K., Greenhaff, P

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315 The expression levels of GLP-1R, PKA/CREB signaling pathway components, and inflammation-related proteins (such as TNF-, IL-1, and IL-6) in the rat knee cartilage tissue were measured using Western blot and immunoprecipitation techniques